Protein Secondary Structure Prediction using Bioinformatics Tools for Hemoglobin
Roma Chandra1, PratibhaTiwari2
1Roma Chandra, Department of Biotechnology, IILM College of Engineering & Technology, Greater Noida.
2PratibhaTiwari, Department of Biotechnology, IILM College of Engineering & Technology, Greater Noida.
Manuscript received on 07 April 2021 | Revised Manuscript received on 03 April 2021 | Manuscript Accepted on 15 April 2021 | Manuscript published on 30 April 2021 | PP: 14-17 | Volume-1 Issue-1, April 2021 | Retrieval Number:100.1/ijaz.A2013041221
Open Access | Ethics and Policies | Indexing and Abstracting
© The Authors. Published by Lattice Science Publication (LSP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Protein structure prediction is one of the important goals in the area of bioinformatics and biotechnology. Prediction methods include structure prediction of both secondary and tertiary structures of protein. Protein secondary structure prediction infers knowledge related to presence of helixes, sheets and coils in a polypeptide chain whereas protein tertiary structure prediction infers knowledge related to three dimensional structures of proteins. Protein secondary structures represent the possible motifs or regular expressions represented as patterns that are predicted from primary protein sequence in the form of alpha helix, betastrand and coils. The secondary structure prediction is useful as it infers information related to the structure and function of unknown protein sequence. There are various secondary structure prediction methods used to predict about helixes, sheets and coils. Based on these methods there are various prediction tools under study. This study includes prediction of hemoglobin using various tools. The results produced inferred knowledge with reference to percentage of amino acids participating to produce helices, sheets and coils. PHD and DSC produced the best of the results out of all the tools used.
Keywords: There are various secondary structure prediction methods used to predict about helixes, sheets and coils.